Only other thing to make sure is that the master/slave jumper on the new drive is set to the same as the old one. Otherwise, it should be a seamless swap.

Personal advice:
You let you 120volt cable plugged in the case, turn the power switch to OFF (or the "O" sign, not the "-"). There, you have your ground.
You ALWAYS put a hand on the case (a metallic part) to discharge any static you might have accumulated (in your body). THEN, with the hand somewhere on the case, you do your work inside the case with the other hand.
Personally, I have one of these $5 bracelets they sell at Radio-Shack : you simply wear it, directly connected to your case so you can use both of your hands.
But just to swap a drive, I'd use the "single hand" method (ie no bracelet). Quicker.

I say that because just ONE discharge and you can screw up
your mobo, memory, CPU, hard drive, etc...
Some might think it's paranoid but I'm very at ease with it and still happy anyway... : )

Thanks everyone for the help! I actually do worry about static electricity discharges, so thanks for the how to, FuTz. I didn't realize I had to do all that though. Guess I need to buy that thing b/c unplugging cables like these requires 2 hands.
As to my second question, is it a tricky thing to put a burner in an external firewire/usb2 enclosure and use it with XP and DVDA2? It would be nice to use it for quicker making of copies and also just to have a portable burner for a laptop.
Thanks for any help!

Musman: I don't have a burner in an external case, but I hear it's done all the time. Firewire is supposedly faster than USB2, though for a DVD burner you don't need very much throughput anyway.

As for static electricity, I have never screwed anything up in my homebrew PC case, and I never bother with a wrist strap. Yes, my office is carpeted, and a touch the metal case before touching anything else, but I've never had to go the "one hand" route. Just touch the case first. I would also unplug the PC completely from the 110v outlet; some PC power supplies don't have a separate mechanical on/off switch, and even if they did, I'd still want the box to be assuredly dead before poking around with a screwdriver.

Thanks for that info. I just checked Video guys and they said the Pioneer 109/A09 is due out later this month. There's always something.

Yep, the idea being getting rid of a possible charge by touching the case. But if you go away from the case, touch it again when you come back.
I wear this thingy when I have to make more serious work in the case. I then put it around my ankle since it's annoying working with that around a wrist.
You can also wear surgical rubber gloves like the ones they sell in drugstores... some folks go that way.

Do not wear gloves. Gloves will act as an insolator, thus allowing your body to store a higher static charge.

The idea behind placing your hand on the metal surface of the grounded power supply case is to ensure that any build-up of electrical charge is bled out of your body. Gloves will defeat this purpose.

If you have never been in your case before, don't use a vacuum cleaner to clean it out, as the dust rubbing against the inside of the of the nozzle and hose can create a static discharge of 1k volts or more. Use only can spray.

It is actually very easy. After you change-out the first one, you'll be an expert.

I think usb2 is a little faster than firewire.

If you're in an office or home office environment, I strongly recommend purchasing anti-static office carpeting (usually available as carpet tiles). It is absolutely impossible to generate ANY static in my office, even if you try. A joy for working on PCs with - zero zap risk. :-)