I have a timeline with MXF file on it, and as soon as I start adjusting track motion, the picture freezes and locks on a frame, and all the track effects don't work anymore.
It's unfortunate, because I was SO excited about how much more stable MKVs are for me in 22. If this is not a known thing, I can try to capture a recreation in a day or two - off back to 21 for now...