I've read that it is a waste of time to defrag disks, but after seeing my system get stuck often during boot, slow opening of programs, and occasional crashes, I used Windows defrag on Drive C. However, it still showed many fragmented files.
So I used some long power leads and a long SATA cable to hook up my boot disk to another computer so that it wouldn't have any open files that would foil the defrag process. THAT really did defrag my disk. After several days, I have not had any mysterious boot problems or crashes and programs definitely open faster.
If you also have maybe 100 programs installed and have used the same Windows installation for a long time (I've used this one for about 18 months) and have uninstalled and re-installed lots of stuff (Vegas 7, various DVDarchitect, media players, DIVX converters, etc. etc.), you might want to do the same.
So I used some long power leads and a long SATA cable to hook up my boot disk to another computer so that it wouldn't have any open files that would foil the defrag process. THAT really did defrag my disk. After several days, I have not had any mysterious boot problems or crashes and programs definitely open faster.
If you also have maybe 100 programs installed and have used the same Windows installation for a long time (I've used this one for about 18 months) and have uninstalled and re-installed lots of stuff (Vegas 7, various DVDarchitect, media players, DIVX converters, etc. etc.), you might want to do the same.