Using VP15 Edit with the latest update, whenever i put in/out point on the timeline and save the project and re load the project later the in/out points are missing. Is there a setting i am missing
No, it does not save in and out points. But you could position a Marker and label them in and out so you can found those points easier when you reload the project.
If you press R on the keyboard, a custom region is marked with "in" and "out" points matching the loop region's "in" and "out" points. Later you can right-click on one of the custom region's tabs and select "select region" from the pop-up menu. The loop region is then placed exactly where the custom region is located. These custom regions are saved. If you hold down the ALT key before you click on a region's tabs, you can move the whole region at once.