Hello!
I have a Vegas 21 Build 315 and when I try to edit a vertical video (HD quality) from my Panasonic GH6, video preview lags to the point where I'm unable to edit, But editing the same type clips that are horizontal works normally. (same setting, file format, resolution, coder). Only difference between clips is that one is horizontal and other is vertical.
I also have the same unusable lag while trying to edit a 4k clip.
I run Windows 11, i9-10900K, 48gb Ram, RTX 3070, and all files are on m2 SSD drive. I don't see why this spec should struggle.