I don't generally use ProRes from 8 bit source and projects, it seems to introduce some pesky shadow noise in sensitive scenes. The noise is not evident in ProRes renders from 10 bit source.
Among 8 bit intermediates I have tried are MagicYUV, MPEG-2, XAVC-I, and Sony YUV, each with their strengths and weaknesses.
What are you using? What do you consider the best tradeoff between size, quality, speed?