Like the title says. I've got a pretty simple timeline--one 8-bit GoPro protune video stream, some titles, some generated solid color media for semi-transparent title backgrounds, and when I switch over to 32/video to render out, pretty much instantly borks my computer. Preview window goes black. Clicking around the timeline gives random black or image with all sorts of weird masking effects.
Oddly enough this doesn't happen in 32/full range, but that mode is just too finicky to work with because of how it alters fx results.
Shifting to GPU in video options seems to clear up the issue, although I have some trust issues when it comes to what appears to be render gliches in GPU mode.
I didn't see anything in the list of known issues. Using i7 Dell 9560 XPS laptop with 16G RAM.