First, I use Vegas Pro 10e, Windows 7 64-bit. I do have Handbrake but haven't used it in a while.
Second, this is for videos to upload to a members-only community (so not processed by YouTube, etc.) but everything I've seen there looks decent. I think most resolutions are full HD 1080p, maybe some 720p.
Third, I believe there is a 2 Gb. file size limit per video. Most of what is there is longer than the first one I will be uploading 8:21 min. (theirs range from 12-30 min.). I prefer to upload at HD 1080p.
Fourth, as some of the old-timers here know, my visual style is rather ethereal to dreamy unlike the more basic-daylight type videos by other members there, hence FX incl. (at times using ParticleIllusion).
Fifth, audio is important for I compose/arrange all my own music. So it has to be at least at 128 to 320 Bps quality (I use 44.1, not 48 Hz).
Last and not least, I'm also someone who tends to do the best I can to do slower-motion (i.e. clip running at 0.7 to 0.5) and a lot of 3-5 seconds "Dissolve" type transitions (not the more choppy no-interval type). Both of these are where artificats can become a problem at times. I work hard to fine tune these. One could say I'm obsessive.
Looks great in Vegas, but can get artifcats-"splotchy" or "blocky" once it's rendered in compressed format. I.e. transitioning from a title or text with gradient type image or background to actual footage.
So to sum this up:
Let's say we have a +/- 10 min. video at HD 1080p that I have rendered out from its master uncompressed AVI.
Q: Which format and settings would you choose to best to minimize artifacts for the compressed upload version?
Thanks.
~ Philip
IMPORTANT SECOND-THOUGHT:
P.S.: Oh, just thought of this too: What should I ask the site in terms of their (I don't know the technical term) their processing "engine" or modality? I know that algorithms can vary widely and knowing the specific platform or software, etc. they use could help in this question being answered here. But it may take a while to get a response from them. So hopefully the posting here as-is will garner some useful wisdom from you.